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Coronavirus Epidemic Update 31: Mortality Rate, Cleaning Products, A More/Less Severe Virus Strain? - YouTube
Channel: MedCram - Medical Lectures Explained CLEARLY
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welcome to another MedCram Covid
nineteen update total confirmed cases
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ninety six thousand total deaths 3300
total recovered fifty three thousands
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going over to the world ometer site
total cases were leveling off now
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starting to pick up we are definitely in
the epidemic face here outside of china
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i like to go to the world ometer for the
latest updates which is on the home page
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and you can see here for March 5th and
of course the day is not done just
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beginning two new cases here in the
United States four new cases in Thailand
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a hundred and forty five new cases in
South Korea they are testing
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aggressively in South Korea as you can
see and if you look at the completed day
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four yesterday you will see two new
deaths in the United States and 34 new
[47]
cases here as well the West Coast is the
place where the epidemic is occurring
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most we have twelve new cases in
Washington State and twelve new cases in
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California five hundred and eighty seven
new cases in just one day in Italy with
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twenty eight new deaths if we look at
the worldwide closed cases we can see
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that the death rate is still falling as
the virus progresses death rate falling
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under six percent we know that the w-h-o
yesterday declared that the world's wide
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estimated case fatality rate is
somewhere at the three percent range
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they had previously said around two
percents looking at active cases that
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are going on right now there about
38,000 of those 32,000 are in mild
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condition probably don't even need to be
in the hospital seventeen percent are in
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serious or critical condition these are
people in the hospital or even in the
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intensive care unit so this is a list
that the EPA is put together of
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registered antimicrobial products for
use against coronavirus SARS cub - the
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cause of kovin 19 this is what we've
been waiting for it was put out on March
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3rd we'll put the link to this in the
description below so you can see that
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bleach and peroxide and certain
chemicals here are to you by the way is
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ready to use and dilute a bowl something
that you can dilute but you can see here
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there's a number of products that
are certified to clean and disinfect
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surfaces that are colonized by the SARS
cub to virus so I want to talk about
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this interesting research article the
research was done by experts at Peking
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University in Beijing Shanghai
University and the Chinese Academy of
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Sciences the gist of the article is we
have the SARS cuff - virus and what
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they're saying is that there's two types
there is an ancestral s type which was
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starting before at the very beginning of
the outbreak and there's been a mutation
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that's branched off the original is
known as the S form and the mutated form
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is known as the L form how they differ
is at a single point where there's been
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a mutation of one nucleotide that's
known as an SNP a single nucleotide
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polymorphism so for instance in the
genome instead of having an a G T which
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would be in the S type the mutated L
version the one that's branched off is
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gonna be a G C at that point there's
been a change of a nucleotide and that's
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caused a difference this L and s form
the S being less severe but the more
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original form was seen only 30% of the
time in wuhan the more severe one ended
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people up in the hospital and they were
quarantine that's been reduced and it's
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been decreasing whereas the 30% one is
the one that seems to be spreading and
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so let's take a look at some of their
data in that article and here is the
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article itself we'll put a link in the
description below and here's a Fulani
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tree where you can see that the red
arrow is the S and the blue arrow the L
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there's also further analysis again the
red dots being the S version and the
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blue dots being the descendants or the
more severe one here you can see the - L
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and s types and you can see that there
is a transition there where the S type
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seems to be more similar to the other
coronaviruses with a T at this position
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in this gene changed to a C and that
became more variant in the L type which
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is the blue one and you can also see it
where this went for instance you can see
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here there's a strain that went to
France
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Germany there's some that have gone to
South Korea the United States the United
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States Singapore Japan but also some of
the s-type has also gone to the United
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States to Australia to Korea Japan etc
etc in terms of the number of strains
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looking at this first part of the graph
outside of Wuhan there was a lot more of
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the s-type whereas inside Wuhan there
was a much much higher concentration of
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the newer l-type which was also more
severe looking at the second part of the
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graph before January 7 versus after
January 7 the s-type was making much
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more of a comeback unfortunately you
can't really choose what form of the
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virus you get infected with and
according to the authors of the study
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you may actually get both apparently the
virus is identified from a patient in
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Australia had multiple degenerated
nucleotides and the best explanation is
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that this patient was infected by at
least two different strains of SARS
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curve two viruses and you can see here
that looking at the two nucleotides at
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these positions they were different even
though this was in the same person of
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course the other possibility is that the
patient may have had mutated viruses in
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them at the same time which is unlikely
the authors and their abstract saying
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that these findings strongly support an
urgent need for further immediate
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comprehensive studies that combine
genomic data epidemiological data and
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chart records of the clinical symptoms
of patients with coronavirus disease
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2019 thanks for joining us
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