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THC vs CBD: What's In Your Weed? - YouTube
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everyone is talking about CBD and THC
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which are two important chemicals found
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in marijuana with marijuana legalization
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becoming mainstream what is the actual
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difference between CBD and THC inside
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you right now there's a biological
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pathway at work called the
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endocannabinoid system that helps
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regulate your mood appetite memory and
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pain sensation THC and CBD though hijack
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this system this is the chemical
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structure of THC also known as
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tetrahydrocannabinol if you are feeling
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fancy and this is the chemical structure
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of CBD also known as cannabidiol what
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you may notice is that their chemical
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structures seem almost identical they
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have the same molecular formula which is
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C 21 H 3002 and both of their masses
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clocking at 314 grams per mole but there
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is one extremely important structural
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difference where THC contains a cyclic
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ring CBD contains a hydroxyl group and
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this difference in biochemistry actually
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controls whether or not you feel high in
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order to fully understand why you need
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to first know about the cb1 receptor in
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your unstoned
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to sober body your cb1 receptor is
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affected by a neurotransmitter called an
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and amide which controls generation of
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pleasure motivation and feeding behavior
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in your unstoned body and manda mine is
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released after exercising and it's what
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causes a runner's high THC structure is
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so similar to Ananda mine that it fits
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in perfectly to the cb1 receptor
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therefore causing you to feel high CBD
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on the other hand because of the
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hydroxyl group is different in shape and
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does not fit into the cb1 receptor
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therefore it doesn't make you feel high
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but CBD does bind to other receptors in
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your cannabinoid system affecting you in
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other ways a lot of excitement came
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around a 2011 study where a few dozen
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people with social anxiety disorder were
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asked to speak in front of a large
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audience some were given CBD some were
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given a placebo those who were given CBD
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reported significantly less anxiety
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there are also many animal studies
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showing CBDs anti-anxiety and
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anti-inflammatory properties which can
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explain why some people say it helps
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with their anxiety and with chronic pain
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research is also discovering that THC
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can actually
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a head Grove eight psychotic symptoms
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while CBD on the other hand may help
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with psychosis so what happens when you
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consume them at the same time one study
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found that due to CBDs biochemical shape
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it can actually bind to the cb1 receptor
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and turn it off in a binding pattern
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known to biologists as allosteric
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inhibition
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this means that CBD actually makes the
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THC unable to bind as well and therefore
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decreases how high you feel if you
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vaporize marijuana with 25% THC and 0.1%
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CBD you will feel high as the THC is
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going to bind to the cb1 receptor with
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little interference from CBD if you
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consume marijuana with 25% THC and 12%
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CBD this more CBD will inhibit the THC
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from binding to the cb1 receptor
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decreasing th DS effect and leading you
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to being less high where marijuana is
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legally sold likely they will indicate
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what percentage of THC and CBD is in the
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product you are choosing which will help
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you to understand the effects that will
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have on your body in the end THC is a
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chemical found in marijuana with a
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chemical structure that makes you feel
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high CBD is a chemical found in
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marijuana with a different chemical
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structure that doesn't make you feel
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high but it can affect your body in
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other less obvious ways there is still
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conflicting research and a lot more to
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understand about both chemicals with
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more states and countries legalizing
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marijuana
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hopefully increased research can uncover
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more details about how these two
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chemicals affect us because weed is now
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legal in Canada we created a new series
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called stoned
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science where we make comedians get high
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and try to explain complex science
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concepts our first episode is about the
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respiratory system so click here to
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watch it and let us know what you think
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as we continue to evolve this new idea
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